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Roast Beef and Cheddar Sandwich

A Roast Beef and Cheddar Sandwich is a take out favorite and so simple to make at home. Smoked roast beef is thinly sliced and piled high on a buttery bun with homemade cheddar sauce and barbecue sauce. A delicious flavor combination for lunch or dinner.

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Roast Beef Sandwich with cheddar sauce on a white plate

Roast Beef and Cheddar Sandwich

I’ve been a long time fan of the Arby’s Beef N’ Cheddar sandwich. I think it’s actually the only thing I have ordered from there.

After making smoked roast beef sandwiches, I knew a beef and cheddar had to happen. We also love these Mushroom and Swiss Roast Beef Sandwiches!

Thin sliced rare roast beef on a cutting board with a knife

Just take me to the Roast Beef and Cheddar Sandwich Recipe!

If you are just looking for the recipe, scroll all the way to the bottom where you will find the printable recipe card. Otherwise, just keep reading for my tips and tricks for making these tasty roast beef sandwiches and the easy homemade cheddar sauce!

Text overlay Roast Beef & Cheddar Sandwich

How to Make Roast Beef and Cheddar Sandwich:

For the Roast Beef:

  1. Use paper towels to pat a chuck roast dry and place on a baking sheet. 
  2. Mix together dry rub with brown sugar, kosher salt, garlic, pepper, smoked paprika and dry mustard. 
  3. Rub over all sides of roast. 
  4. Prepare grill to about 300- 350°.Chuck roast on a wood fired grill
  5. Place Roast over prepared grill and close the grill.
  6. Cook for about 15 minutes per pound until 128-135° internal temperature for rare, 145° for medium.Grilled Chuck Roast on a baking sheet
  7. Remove from grill and cover with foil. Allow to rest 15 minutes before slicing thin. You may also wrap the roast in plastic wrap and refrigerate until completely chilled to slice. 

How to make homemade cheddar cheese sauce, collage

For the Cheddar Sauce:

  1. In a heavy bottom pan, melt butter and add in all purpose flour, dry mustard, salt and pepper. Whisk to combine. 
  2. Cook for 3 minutes and whisk in milk and continue cooking about 5 minutes over medium heat until thickened. 
  3. Remove from heat and stir in cheese until completely melted. Cheddar Cheese Sauce in a sauce pan, spoon drizzling cheese

Assemble the Roast Beef and Cheddar Sandwiches:

  1. Toast buns lightly and brush with garlic and onion butter. 
  2. Top buns with barbecue sauce, thinly sliced roast beef, cheddar sauce and top bun. 

Rare roast beef sandwich on a bun with cheddar cheese sauce

If you have a pressure cooker, this Instant Pot Beef and Cheddar is a great one to try.

Best Barbecue Sauce for Roast Beef Sandwiches:

Dr Pepper Barbecue Sauce is sweet and delicious and always a favorite for grilled meats. 

Homemade Barbecue Sauce is sweet and tangy. It’s a thick and hearty sauce perfect for burgers and sandwiches. 

Jalapeño Barbecue Sauce is great if you like a little kick to your barbecue!

We also love adding this homemade Horseradish Sauce to a roast beef sandwich!

Delicious Dishes to Serve with Roast Beef Sandwiches:

Oven Fried Tater Tots are so easy to make in the oven, no worries about the deep frying. These tater tots have a secret ingredient that makes them super crispy and flavorful!

Easy Onion Strings are always a hit with burgers and sandwiches. Serve them on the sandwich or on the side. 

The Best Macaroni Salad is a staple for any family get together. It has a sweet dressing and is filled with crunchy veggies. 

Fried Okra is another favorite side dish, my kids beg for it and it’s super simple to make at home. 

Collage sliced roast beef, roast beef sandwich

We are huge fans of a Sunday pot roast and this Rump Roast with our homemade Beef Rub is a great one to add to your dinner list. It would also make amazing sandwiches. These Poor Man’s Burnt Ends are also a great dinner to make with a chuck roast. 

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Yield: 8 servings

Roast Beef and Cheddar Sandwich

Roast Beef Sandwich with cheddar sauce on a white plate

A Roast Beef and Cheddar Sandwich is a take out favorite and so simple to make at home. Smoked roast beef is thinly sliced and piled high on a buttery bun with homemade cheddar sauce and barbecue sauce. A delicious flavor combination for lunch or dinner.

Prep Time 10 minutes
Cook Time 1 hour
Total Time 1 hour 10 minutes

Ingredients

  • For the Roast Beef:
  • 4 pound beef chuck roast
  • 1/4 cup brown sugar
  • 1 teaspoon kosher salt
  • 1 teaspoon black pepper
  • 1 teaspoon granulated garlic
  • 1 teaspoon smoked paprika
  • 1 teaspoon dry mustard
  • For the Cheese Sauce:
  • 2 tablespoons butter
  • 2 tablespoons all purpose flour
  • 1/4 teaspoon kosher salt
  • 1/4 teaspoon dry mustard
  • 1/4 teaspoon black pepper
  • 1 cup milk
  • 2 cups shredded cheddar cheese
  • For the Sandwiches:
  • 1/2 cup barbecue sauce
  • 8 sandwich buns
  • 2 tablespoons of melted butter
  • 1/2 teaspoon onion flakes
  • 1/4 teaspoon granulated garlic

Instructions

For the Roast Beef:

  1. Pat roast with paper towels and place on a baking sheet. 
  2. Mix dry rub in a small bowl: brown sugar, kosher salt, garlic, pepper, smoked paprika and dry mustard. 
  3. Rub over all sides of roast. 
  4. Heat grill to about 300- 350°.
  5. Place Roast on grill and close the grill.
  6. Cook roast for about 15 minutes per pound until 128-135° internal temperature for rare, 145° for medium.
  7. Remove from grill and cover with foil. Allow to rest 15 minutes before slicing thin. You may also wrap the roast in plastic wrap and refrigerate until completely chilled to slice.

For the Cheddar Sauce:

  1. Melt butter in a saucepan and whisk in flour, dry mustard, salt and pepper.
  2. Cook for 3 minutes, whisking continually. Add milk and continue cooking about 5 minutes over medium heat until thickened. 
  3. Remove from heat and stir in cheese until completely melted. 

Assemble the Roast Beef and Cheddar Sandwiches:

  1. Lightly toast buns
  2. Mix melted butter with onion flakes and garlic, brush tops with butter while warm.
  3. Top buns with barbecue sauce, thinly sliced roast beef, cheddar sauce and top bun.

Nutrition Information:

Yield:

8

Serving Size:

1

Amount Per Serving: Calories: 970Total Fat: 56gSaturated Fat: 26gTrans Fat: 3gUnsaturated Fat: 26gCholesterol: 250mgSodium: 1259mgCarbohydrates: 44gFiber: 2gSugar: 12gProtein: 73g

Nutritional calculations are estimated and may not be accurate.

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