Preheat oven to 375°.
Mix biscuit crust together in a large bowl, combining flour, sugar, baking powder and salt.
Add butter and shortening and cut into flour with a fork until mixture is crumbly.
Stir in buttermilk until dough comes together.
Spray a 9 x 13 inch baking dish with non stick cooking spray.
Pour dough into pan and sprinkle with a little flour and spread the dough evenly over bottom and just slightly up the sides of the pan.
Bake for 20 minutes or until lightly browned. Crust may puff up a bit, that is okay.
While the crust bakes, whisk eggs, milk, cream, 3/4 cup of mozzarella cheese, salt, pepper and red pepper flakes in a large bowl and set aside.
Prepare the sauce by combining pasta sauce with sugar, oregano, basil and thyme in a small bowl, set aside.
Cook sausage over medium heat in olive oil, stirring often to break up and brown on all sides. Add onions, peppers and mushrooms and continue to cook until vegetables are softened.
Remove biscuit crust from oven and top with egg mixture. Return to oven for 35 minutes or until eggs are set.
Remove from oven and spread pizza sauce over egg layer. Top with cooked sausage and vegetable mixture. Top with mozzarella and colby jack cheese.
Bake for 10 minutes or until cheese is melted and bubbly.
Allow casserole to rest 5 minutes before serving.